Full Metal Alchemist kicks ass. It's been a while since I've run into an anime this original, and this well fleshed-out. And yes, while it can get a little heavy on the moralizing at times, the dialogue is snappy, and the plots well-paced.
I especially like how he looks up at the end, sings a bit, plays a little summary, then plays a little more, as if going--is this alright? And how about this? Yeah?