http://www.a-ztech.it/rhino.htm Not sure if the above revolver is real, soon to be real, or just fictitious all together but I would love to have a revolver that aligned the barrel with the bottom most chamber in the cylinder rather than the upper most.
I know for sure one revolver of this configuration exists the Mateba Auto-Revolver but due to the auto cyclying part of this weapon the bore axis is really not any lower than a good semi auto.
The Rhino above put the axis of the bore in line with your forearm. muzzle flip during recoil would be nonexistent.