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"Grading is notoriously difficult to perform reproductively and depends heavily on experience and understanding of the criteria of the categories. The latter problem often means it is to easier to invent one's own classification than to abide by another's"Donald Skinner MD, 1971.
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Rather banal, but so true.
Knowledge of the ideal specimen will enhance recognition of structures in the disrupted specimen.
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Cell Whisper
"A specific range of temperature and pH allow biochemical reactions to proceed within our body. Prolonged hypoxia may not kill instantly, but makes cells function in an anaerobic way, creating metabolites (lactic acid, H+, CO2) that will drop outside of the normal range of the “milieu interieur.” Loss of that warm red fluid will cause de facto ( Read more... ) -
Интересная мысль...
An excerption from comments to discussion of an article "Is it cancer or a lesion" by Thomas Wheeler, MD, Pathology, Aug 2, 2013 published on www.medscape.com/pathology
Added By: jpetrucci1, MD, Pathology, 03:25PM Aug 13, 2013
"The term Ca in-situ is an oxymoron. It 1s equivalent to a "virgin-prostitute. A lesion without invasion will ( Read more... ) -
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"Immunohistochemistry has become the surgical pathologist’s “second H&E” and is invaluable in assessing tumour type, prognosis and potential response to treatment."
"Histopathology Reporting Guidelines for Surgical Cancer"
Second Edition by Derek C. Allen
