(Untitled)

[krk]

Whew. Another semester survived. I am D-O-N-E. Onto packing and moving

Comments

[palebluedots]

Yes I read the entire thing (twice, as a matter of fact) and yes, I enjoyed it. I didn't understand every word of what was happening, but I still found it fascinating that there can be two types of protein folds for ARNT that are equally possible -- just that one is usually favoured by evolutionary selection.

Are there any instances where the protein you studied -- if it's malformed -- would cause neurological or other damage?

[krk]

Oh probably. Could cause death.

The case where Ltn is in equilibrium with it's two forms (Ltn10 and Ltn40) and both are biologically active is FACINATING. It's the first case I am aware of this happening and I think the first time this has been found. The usual structure determination of the protein structure using Xray crystallography did not show both conformations. So there may be a TON of proteins with similar properties but because of the determination via crystallography we don't know. So quite revolutionary. :)

[palebluedots]

Biology iz fun. :P

Yeah, and maybe at some point we ("we" being the royal "we" of science which actually means people like you) will figure out how to fold malformed proteins in the right way to prevent damage, too. Maybe you'll discover that! :)

[krk]

I wish - would make me a lot of money or make me famous forever. Probably poor and famous. ;)

[cicero_in_pants]

Congrats on finishing the semester! Happy moving!! :)

[krk]

Shhh...my brain hasn't realized I am moving so I am not stressed yet.

[cicero_in_pants]

But...but... you said it right in the post!!! O_O

[krk]

Still in this weird denial zone. :) Need a day not thinking. :D

You should see this place - it is GIANT. Bigger than your apartment was. Bigger than Andrew's...It is sweet.

[sideris]

woot woot!