...So. Far. Behind. Also, these numbers are annoyingly all out of order. What I'm calling "book 18" I finished yesterday; what I'm calling "book 19" I finished in October. Ergh.
18. Raj Patel, Stuffed and Starved: The Hidden Battle for the World's Food System.Wide-ranging, engaging analysis (from a systems perspective!) of the global markets in
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It seems like this is another element tempting drug companies to seek test subjects among populations that have no access to health care. If they want to test a placebo, but they can't do it with subjects who are already getting the existing treatment, use subjects who aren't getting any treatment at all.
There are at least two ethical standards concerning experimental subjects: one is local and relativistic (the experimental subjects should be no worse off from participating in the experiment than they would have been had they declined to participate)I'm familiar with the relativistic standard from university research situations. The way it was explained in the training I had to take was that you can compensate ( ... )
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Absolutely. It's difficult to find subjects for HIV trials stateside, because the existing treatments already work pretty well. Who would give up an existing, effective treatment to roll the dice on an untried one? And what drug company wants to put their proposed drug up against a proven treatment, when they only need to show that they are better than a placebo?
Whether or not it's acceptable to do placebo-controlled out-of-country studies is another matter, though. International ethical standards have relaxed on that point during the past decade; prior to that, the Declaration of Helsinki (if I'm getting my various standards documents correct) appeared to prevent the use of placebos in out-of-country studies when a treatment existed in the originating country. Revisions in 2000 appeared to codify the permissibility of placebos out-of-country even when ( ... )
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Sex and race are more incidental to Patel's analysis -- basically, Patel inserts notes that race or sex comes into play in this part of the discussion in a particular way. So race and sex aren't treated extensively, but he does give info that they do come into play, and (if you go into the endnotes) there are resources which expand upon that particular item.
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