Carraguard Shows Promising Results
http://hpv2010.org/main/index.php?option=com_conference&view=presentation&id=1110&conference=1&Itemid=100
Results: ...After adjusting for risk factors, Carraguard was found protective for HPV infection for women who inserted >80% of their returned applicators of test product with >30% confirmed covered sex acts. Within the latter category, Carraguard was almost 50% more efficacious than placebo. Carraguard users were 0.529 as likely to contract HR-HPV [95% CI (0.304, 0.920)] as women who used placebo (P=0.0176).
Conclusions: Carraguard was shown to be effective in protecting against vaginal transmission of HR-HPV. To our knowledge, this is the first report of successful protection against genital infection by a vaginal microbicide.
We haven't seen much lately about the carrageenan studies for use as a topical preventative for HPV. Last I'd heard, they were going to human trials and the results were supposed to be out early last year, but I haven't found anything, one way or the other, until now. This particular brand that this study was testing, was found to have failed its anti-HIV test, and I posted about it at the time that I feared they would not follow up on its anti-HPV properties.
Well, apparently someone did, and it seems to be holding up against HPV. I'm still looking out for BufferGel, which was my favorite of the brands being considered, so when I hear more, I'll let ya'll know!
Results: ...After adjusting for risk factors, Carraguard was found protective for HPV infection for women who inserted >80% of their returned applicators of test product with >30% confirmed covered sex acts. Within the latter category, Carraguard was almost 50% more efficacious than placebo. Carraguard users were 0.529 as likely to contract HR-HPV [95% CI (0.304, 0.920)] as women who used placebo (P=0.0176).
Conclusions: Carraguard was shown to be effective in protecting against vaginal transmission of HR-HPV. To our knowledge, this is the first report of successful protection against genital infection by a vaginal microbicide.
We haven't seen much lately about the carrageenan studies for use as a topical preventative for HPV. Last I'd heard, they were going to human trials and the results were supposed to be out early last year, but I haven't found anything, one way or the other, until now. This particular brand that this study was testing, was found to have failed its anti-HIV test, and I posted about it at the time that I feared they would not follow up on its anti-HPV properties.
Well, apparently someone did, and it seems to be holding up against HPV. I'm still looking out for BufferGel, which was my favorite of the brands being considered, so when I hear more, I'll let ya'll know!