That "no good reason" thing, for me, turned out to be Bipolar. You should chart your ups and downs. If there is a pattern, whether in months or hours,of ups and downs, you should really be checked for bipolar. In the meantime, consider some kind of counseling, if you aren't in it already. Please.
*offers hugs* I am sorry to hear you're having such a hard time. Depression is so difficult. You mention it might likely be chemical. Do you think part of it might be some sort of rebound effect from having many overwhelming positive experiences in your life recently? Just a wondering thing, not trying to suggest that I know why you're experiencing what you are.
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I only have hugs to offer. And love. ♥
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