Some single-season records

[pmw]

400+ Total Bases (29 times):
Lou Gehrig (5) 1927, 1930, 1931, 1934, 1936
Chuck Klein (3) 1929, 1930, 1932
Babe Ruth (2) 1921 (all-time record: 457), 1927
Rogers Hornsby (2) 1922, 1929
Jimmie Foxx (2) 1932, 1933
Sammy Sosa (2) 1998, 2001
Todd Helton (2) 2000, 2001
11 others, once each

100+ Extra-Base Hits (15 times):
Lou Gehrig (2) 1927, 1930
Chuck Klein (2) 1930, 1932
Todd Helton (2) 2000, 2001
9 others, once each, including Babe Ruth 1921 (all-time record: 119)