I think
this article may be about Uncle Bruce.
I'm not quite sure how to get my hands on it, though.
The subject of this entry is what caused all his problems.
I know he had pure red cell aplasia (PRCA) and lichen planus.
However, I'm not completely sure he has
hypogammaglobulinemia (or, more broadly, CVID), though it appears he had some of the symptoms.
For example, he had chronic lung/chest infections and sinusitis. I believe he may have had
bronchiectasis, also commonly associated with this. The poor guy constantly had to cough up sputum in his last couple of years. He'd have to pound on his back to loosen the sputum and cough it up.
In addition, his body attacked the red blood cells it made (which is autoimmune), which also can happen with hypogammaglobulinemia.
This article, from Japan, is about a man with pure red cell aplasia and
Good's Syndrome. I haven't read all of it yet, but some if it may be similar to his case as well.
Good Syndrome appears to be very similar to, if not the same as, hypogammaglobulinemia.
Well, the first article I mentioned was written by surgeons from the Mayo Clinic in Rochester, MN. It was published in 1994. Around 1990, my uncle's thymoma was removed (8 pounds!), and this 4 year gap makes sense for them to further analyze his progress (or lack there of) and symptoms. Plus, they have to submit it before it is published.
So, I'd like to get my hands on that article, titled "Lipothymoma with red cell aplasia, hypogammaglobulinemia, and lichen planus." The authors are KG McManus, MS Allen, VF Trastek, C Deschamps, TB Crotty and PC Pairolero of the Section of General Thoracic Surgery, Mayo Clinic, Rochester, Minnesota 55905. This was published in the following Journal: The Annals of Thoracic Surgery, Vol 58, 1534-1536, Copyright © 1994 by The Society of Thoracic Surgeons.
I really should get to bed.