Sis #2 and I were watching a promotional clip for Resident Evil: Retribution on TV a few days ago, and it mentioned that Michelle Rodriguez would be returning as Rain, who was shot in the head in the first film. (The reason for her return was never explained, and while I knew what it was, I didn't tell Sis #2 because it can be considered a spoiler, I suppose, and I'm not too sure what it entails either.) Sis #2 expressed confusion, and then added, "You know who won't -- can't? -- return? The guy who was cubed by lasers [One]."
Nope, I didn't tell her either. Some things are best found out on their own.