Buffalo Bills will play against Indianapolis Colts in 2010 NFL Preseason . The Colts care they lost 37-17 at home to the San Francisco 49ers in their first preseason game. While, the Bills win the Washington Redskins 42-17 in their opener. The Colts quarterback is Peyton Manning starts, Curtis Painter and Tim Brandstater. Buffalo’s Ryan Fitzpatrick ( Read more... )