I would go with early in the day for the b12 and the magnesium at night. At uni when we were studying vitamins and minerals the protocol for prescribing would usually be 'Vitamins in the morning, minerals at night.' It because the b12 provides extra energy and is better to be administered when you are going to use it. It also might make you a bit more alert, I've heard of people being too awake to sleep if they took b12 vitamin at night. And Magnesium is better to take before bed as it relaxes the muscles and should help your sleep.
Good luck with them, I'm planning on starting a similar routine (I already do the mag when I remember, but am going to start b12 injections instead of sublinguals. Can I ask what your form your magnesium supplement is? Are you taking calcium with it? Because that usually is a good idea.
It's buffered magnesium glycinate, I already take a calcium supplement and a D supplement at night time on account of osteoporosis/osteopaenia (from prednisolone for Crohn's Disease).
I've now taken a couple of doses of the magnesium, and I'm now doing them in the morning for a few days because they *might* have affected my gut and I figure taking them in the day time is easier until I work that out.
I wouldn't be surprised if the magnesium doesn't work out well with your poor GIT. I was talking to someone at the CFS/ME meet up that had great results with the injections because supplements hurt his gut too much. It's on my to-do to explore list when I have a GP I like!
I've given them to myself *shudder* many times, and haven't found it to disrupt sleeping patterns, if anything, taking regular injections seems like it helps my sleep.
I give them to myself whenever I work up the energy to, but it seems to be best to do for me in the afternoons, when I need more of a boost. A little folic acid, for me, along with B12 is even better.
I take Mg supplements regularly throughout the day. Is this IM or pill?
B Vitamins should be taken in the morning, as they help to metabolize, offer a slight mood boost, and generally "kick it up" a notch body-wise.
Some things to keep in mind-- the injection site, because your body (especially one side if you have myofacial pain syndrome which is common with M.E.-- on top of fibro, etc.) will respond to pain differently. So, plan carefully.
Finally, it may well be that the B-vitamin injections won't help. They only really help if you have serious vitamin deficiencies (like athletes who don't eat right or drink too much alcohol, which washes it out.) You'll know within a day or 2 at most if it's working. People who have B deficiency and take injections notice a profound difference within hours in most cases. This isn't one of those slow-over-time needed in order to test effectiveness type of things. If it works, you'll know pretty fast!
If splodge is with my Doc which I suspect she is, the B12 is being given not for a deficinecy but to lower the levels of nitric oxide. It has started many of his patients off feeling sore & exhausted afterwards, and as they build it up it starts to have a positive effect. Something to do with the nitric oxide dying off and leaking the die-off into the system making you feel crap, then there's less to kill off. Can't rememeber, I stopped taking it (focusing on another treatment), but you won't know in 2-3 days and it's not for a deficiency. And it has helped a lot of his patients a huge amount - even if it made them feel a bit worse for the first month.
I can see, given this information, that waiting a good 3 days to see if it's working makes sense. However, B vitamins are all water soluable, which means they break up in the body within hours. It wouldn't take a month or longer to accomplish a nitric oxide cleansing, which would flush out of the system within a mere few days.
This illness effects multiple systems, so it's not often that one solution addresses all the problems. In such complex situations, I'm always wary of quacks and charlatans trying to take advantage of the situation. A month of B vitamin shots doesn't make sense.
I do my B12 injections once a week and I do it at night.. In the tush.. I tried doing it in the arm (tricep), but my arm would go numb/dead.. so in the tush is the least annoying.. It doesnt hurt at all.. You will get used to inkecting yourself!
How often will you be doing the injections?
Honestly, I was told by my doc it makes no difference what time of day.. Just a matter of convenience...
I used to do injections but switched to sublingual tablets because my thighs were gettting lumpy and bumpy and once I hit and area I guess where a nerve runs...it didn't hurt, just that area went numb for a while. I asked my doctor about it and she's the one that told me a nerve runs there and it's also along an acupuncture meridian
( ... )
oh, when I said telomeres are like shoelaces, I meant they get "cut" or shortened every time a cell divides. The less Mg you have the faster they'll shorten.
Eventually I'm supposed to be taking two capsules a day of the magnesium, so as long as it doesn't upset my stomach, I guess I'll probably take one at morning, one at night.
I'm currently on sublingual b12, but my doc seems to think this will have more an effect. I take b6 as well, but hadn't given any thought to folic acid, so thanks for the warning.
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Good luck with them, I'm planning on starting a similar routine (I already do the mag when I remember, but am going to start b12 injections instead of sublinguals. Can I ask what your form your magnesium supplement is? Are you taking calcium with it? Because that usually is a good idea.
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I've now taken a couple of doses of the magnesium, and I'm now doing them in the morning for a few days because they *might* have affected my gut and I figure taking them in the day time is easier until I work that out.
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Me too.
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I give them to myself whenever I work up the energy to, but it seems to be best to do for me in the afternoons, when I need more of a boost. A little folic acid, for me, along with B12 is even better.
I take Mg supplements regularly throughout the day. Is this IM or pill?
Reply
Reply
Some things to keep in mind-- the injection site, because your body (especially one side if you have myofacial pain syndrome which is common with M.E.-- on top of fibro, etc.) will respond to pain differently. So, plan carefully.
Finally, it may well be that the B-vitamin injections won't help. They only really help if you have serious vitamin deficiencies (like athletes who don't eat right or drink too much alcohol, which washes it out.) You'll know within a day or 2 at most if it's working. People who have B deficiency and take injections notice a profound difference within hours in most cases. This isn't one of those slow-over-time needed in order to test effectiveness type of things. If it works, you'll know pretty fast!
Finally-- good luck. I hope it helps.
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:-)
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If splodge is with my Doc which I suspect she is, the B12 is being given not for a deficinecy but to lower the levels of nitric oxide. It has started many of his patients off feeling sore & exhausted afterwards, and as they build it up it starts to have a positive effect. Something to do with the nitric oxide dying off and leaking the die-off into the system making you feel crap, then there's less to kill off. Can't rememeber, I stopped taking it (focusing on another treatment), but you won't know in 2-3 days and it's not for a deficiency. And it has helped a lot of his patients a huge amount - even if it made them feel a bit worse for the first month.
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This illness effects multiple systems, so it's not often that one solution addresses all the problems. In such complex situations, I'm always wary of quacks and charlatans trying to take advantage of the situation. A month of B vitamin shots doesn't make sense.
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How often will you be doing the injections?
Honestly, I was told by my doc it makes no difference what time of day.. Just a matter of convenience...
Good luck!
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It's Sunday night.. time for my injection right now! ;)
*HUGS*
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It just occurred to me that injecting oneself in the tush would require a certain degree of flexibility. I am impressed. ;-)
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Eventually I'm supposed to be taking two capsules a day of the magnesium, so as long as it doesn't upset my stomach, I guess I'll probably take one at morning, one at night.
I'm currently on sublingual b12, but my doc seems to think this will have more an effect. I take b6 as well, but hadn't given any thought to folic acid, so thanks for the warning.
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