Orion Williamson was a Selma, Alabama farmer who, on a July day in 1854, simply vanished into thin air while walking across his property. What makes this case especially notable is the fact he did so in full view of his wife and son, as well as two other witnesses (neighbor Armour Wren and his son James).
The Wrens, who'd been riding along a road on the other side of the field in a horse and buggy, immediately ran to the spot where Williamson had last been seen, idly swishing the ankle-deep grass with a small stick, but found nothing. Most of the grass was gone from the spot where Williamson had disappeared as well. The news was quickly carried into town, and soon three hundred men formed a massive search party. They combed the field in three rows an arm length apart from each other, but their thorough search yielded no clues. As news of the inexplicable event spread for miles around Selma, hundreds of curious onlookers arrived at the farm to join in the futile search or merely to gawk at the scene. A geologist and a team of experts dug up the field to see if perhaps the ground underneath was unstable or abnormal at all. They found nothing unusual.
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Worson was a shoemaker who lived in Warwickshire, England. He was prone to bragging about his prowess as a long-distance runner, and on September 3, 1873, he was challenged by two friends, linen draper Barham Wise and photographer Hamerson Burns, to run the 40 mile distance from Leamington to Coventry. Worson accepted and started jogging while his friends followed closely in a horse-drawn cart. Worson ran easily for several miles, conversing along the way with his friends. Suddenly, when he was only a half dozen yards from them, and with their eyes fixed upon him, Worson appeared to stumble in the middle of the road. He then fell forward and, as he went down, gave out an awful cry of terror. He then vanished completely. Burns and Wise searched frantically, but couldn't find a trace of their friend who appeared to have evaporated into thin air right before their eyes. A subsequent extensive search of the area yielded similar results, and Corson was never seen again.
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Owen Parfitt had been paralyzed by a massive stroke. In June, 1763 in Shepton Mallet, England, Parfitt sat outside his sister's home, as was often his habit on warm evenings. Virtually unable to move, the 60-year-old man sat quietly is his nightshirt upon his folded greatcoat. Across the road was a farm where workers were finishing their workday by pooking the hay. At about 7 p.m., Parfitt's sister, Susannah, went outside with a neighbor to help Parfitt move back into the house, as a storm was approaching. But he was gone. Only his folded greatcoat upon which he sat remained. Investigations of this mysterious disappearance were carried out as late as 1933, but no trace or clues to Parfitt's fate were ever uncovered.
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British diplomat Benjamin Bathurst vanished into thin air in 1809. Bathurst was returning to Hamburg with a companion after a mission to the Austrian court. Along the way, they had stopped for dinner at an inn in the town of Perelberg. Upon finishing the meal, they returned to their waiting horse-drawn coach. Bathurst's companion watched as the diplomat stepped over to the front of the coach to examine to horses - and simply vanished without a trace.
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In 1975, a man named Jackson Wright was driving with his wife from New Jersey to New York City. This required them to travel through the Lincoln Tunnel. According to Wright, who was driving, once through the tunnel he pulled the car over to wipe the windshield of condensation. His wife Martha volunteered to clean off the back window so they could more readily resume their trip. When Wright turned around, his wife was gone. He neither heard nor saw anything unusual take place, and a subsequent investigation could find no evidence of foul play. Martha Wright had just disappeared.
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The year was 1815 and the location a Prussian prison at Weichselmunde. The prisoner's name was Diderici, a valet who was serving a sentence for assuming his employer's identity after he died from a stroke. It was an ordinary afternoon and Diderici was just one in a line of prisoners, all chained together, walking in the prison yard for the day's exercise. As Diderici walked with his prison inmates to the clanking of their shackles, he slowly began to fade - literally. His body became more and more transparent until Diderici disappeared altogether, and his manacles and leg irons fell empty to the ground. He disappeared into thin air and was never seen again.
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And then there's all the stories of whole villages or colonies just disappearing, and a storm that made a group of hippies disappear in Stonehenge in the 70s but left all their camping things and there was weird blue light from the stones and screaming.
I don't know.
Also:
I found this from 2006. It's not quite 'vanished into thin air' but it's really really close.