Pineapple The exceptional juiciness and vibrant tropical flavor of pineapple that balances the tastes of sweet and tart make them only second to bananas as America’s favorite tropical fruit. Although the season for pineapple runs from March through June, they are available year-round in local markets.
HA Digestive Aid and A Natural Anti-Inflammatory Fresh pineapple is rich in bromelain, a group of sulfur-containing proteolytic (protein-digesting) enzymes that not only aid digestion, but can effectively reduce inflammation and swelling, and has even been used experimentally as an anti-cancer agent. A variety of inflammatory agents are inhibited by the action of bromelain. In clinical human trials, bromelain has demonstrated signifcant anti-inflammatory effects, reducing swelling in inflammatory conditions such as acute sinusitis, sore throat, arthritis and gout, and speeding recovery from injuries and surgery. To maximize bromelain’s anti-inflammatory effects, pineapple should be eaten alone between meals or its enzymes will be used up digesting food.
Antioxidant Protection and Immune Support Vitamin C is the body's primary water-soluble antioxidant, defending all aqueous areas of the body against free radicals that attack and damage normal cells. In this study, which involved 77,562 women and 40,866 men, researchers evaluated the effect of study participants' consumption of fruits; vegetables; the antioxidant vitamins A, C, and E; and carotenoids on the development of early ARMD or neovascular ARM, a more severe form of the illness associated with vision loss. Food intake information was collected periodically for up to 18 years for women and 12 years for men. While, surprisingly, intakes of vegetables, antioxidant vitamins and carotenoids were not strongly related to incidence of either form of ARM, fruit intake was definitely protective against the severe form of this vision-destroying disease. Three servings of fruit may sound like a lot to eat each day, but pineapple can help you reach this goal. Add fresh pineapple to your morning smoothie, lunch time yogurt, any fruit and most vegetable salads. For example, try adding chunks of pineapple to your next cole slaw or carrot salad. For an elegant meal, top any fish with teriyaki sauce and fresh sliced pineapple, then broil.
Anti-Tumor Compounds Found in Pineapple Stems Two molecules found in pineapple stems have shown anti-tumor activity in research done at Australia's Queensland Institute of Medical Research. One of the molecules, called CCS, blocks the Ras protein, which is defective in approximately 30% of all cancers, while the other molecule, CCZ, stimulates the immune system to target and eliminate cancer cells.
According to the National Cancer Institute, cancer has now overtaken cardiac disease as the largest killer in the U.S. Cancer incidence increases with age, with approximately 80% of cancers occurring in people over the age of 55. The major limitation of current cancer therapies is they are non-specific and affect both normal and tumor cells. Future cancer treatments will be highly specific to selectively destroy the cancer cells, counteracting the mechanisms by which cancers grow. Data already generated show that CCS and CCZ have the desired specificity and selectivity.
"An interesting characteristic of CCS and CCZ is that they are proteases."The way CCS and CCZ work is different to any other drug in clinical use today. Therefore, CCS and CCZ will represent a totally new way of treating disease and potentially a whole new class of anti-cancer agent. In general, products with novel mechanisms of action are more likely to represent real breakthroughs in the treatment or prevention of disease." QIMR is continuing to investigate CCS and CCZ to demonstrate i) additional in vivo proof of principle, ii) reliable supply of the material and iii) safety. All these factors will be addressed in a two year research program. If all the objectives of the research are achieved, CCS or CCZ will rapidly progress to human clinical trials.
The exceptional juiciness and vibrant tropical flavor of pineapple that balances the tastes of sweet and tart make them only second to bananas as America’s favorite tropical fruit. Although the season for pineapple runs from March through June, they are available year-round in local markets.
HA Digestive Aid and A Natural Anti-Inflammatory
Fresh pineapple is rich in bromelain, a group of sulfur-containing proteolytic (protein-digesting) enzymes that not only aid digestion, but can effectively reduce inflammation and swelling, and has even been used experimentally as an anti-cancer agent. A variety of inflammatory agents are inhibited by the action of bromelain. In clinical human trials, bromelain has demonstrated signifcant anti-inflammatory effects, reducing swelling in inflammatory conditions such as acute sinusitis, sore throat, arthritis and gout, and speeding recovery from injuries and surgery. To maximize bromelain’s anti-inflammatory effects, pineapple should be eaten alone between meals or its enzymes will be used up digesting food.
Antioxidant Protection and Immune Support
Vitamin C is the body's primary water-soluble antioxidant, defending all aqueous areas of the body against free radicals that attack and damage normal cells.
In this study, which involved 77,562 women and 40,866 men, researchers evaluated the effect of study participants' consumption of fruits; vegetables; the antioxidant vitamins A, C, and E; and carotenoids on the development of early ARMD or neovascular ARM, a more severe form of the illness associated with vision loss. Food intake information was collected periodically for up to 18 years for women and 12 years for men. While, surprisingly, intakes of vegetables, antioxidant vitamins and carotenoids were not strongly related to incidence of either form of ARM, fruit intake was definitely protective against the severe form of this vision-destroying disease. Three servings of fruit may sound like a lot to eat each day, but pineapple can help you reach this goal. Add fresh pineapple to your morning smoothie, lunch time yogurt, any fruit and most vegetable salads. For example, try adding chunks of pineapple to your next cole slaw or carrot salad. For an elegant meal, top any fish with teriyaki sauce and fresh sliced pineapple, then broil.
Anti-Tumor Compounds Found in Pineapple Stems
Two molecules found in pineapple stems have shown anti-tumor activity in research done at Australia's Queensland Institute of Medical Research. One of the molecules, called CCS, blocks the Ras protein, which is defective in approximately 30% of all cancers, while the other molecule, CCZ, stimulates the immune system to target and eliminate cancer cells.
According to the National Cancer Institute, cancer has now overtaken cardiac disease as the largest killer in the U.S. Cancer incidence increases with age, with approximately 80% of cancers occurring in people over the age of 55. The major limitation of current cancer therapies is they are non-specific and affect both normal and tumor cells. Future cancer treatments will be highly specific to selectively destroy the cancer cells, counteracting the mechanisms by which cancers grow. Data already generated show that CCS and CCZ have the desired specificity and selectivity.
"An interesting characteristic of CCS and CCZ is that they are proteases."The way CCS and CCZ work is different to any other drug in clinical use today. Therefore, CCS and CCZ will represent a totally new way of treating disease and potentially a whole new class of anti-cancer agent. In general, products with novel mechanisms of action are more likely to represent real breakthroughs in the treatment or prevention of disease." QIMR is continuing to investigate CCS and CCZ to demonstrate i) additional in vivo proof of principle, ii) reliable supply of the material and iii) safety. All these factors will be addressed in a two year research program. If all the objectives of the research are achieved, CCS or CCZ will rapidly progress to human clinical trials.
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