Found on BuddyTV -- to celebrate Supernatural reaching its 100th episode, they put together 100 funniest quotes from the show.
Here's just a few of my favorites from each season:
"Dude, you fugly" Dean to the scarecrow in season 1's "Scarecrow"
Dean: "Of course, the most troubling question is why do these people assume we're gay?"
Sam: "Well, you are kind of butch. They probably think you're overcompensating."
-from season 2's "Playthings"
Dean: "Hey, Ed, listen to me. There's some salt in my duffel. Make a circle and get inside."
Ed: "Inside your duffel bag??
Dean: "In the salt, you idiot!"
-from season 3's "Ghostfacers"
“Brother, I have been re-hymenated and the dude will not abide.”
-Dean in season 4’s “Monster Movie"
Becky: "And then Sam touched..." No. "...caressed Dean's clavicle. 'This is wrong,' said Dean. 'Then I don't want to be right,' replied Sam, in a husky voice."
-writing slash fan fiction in season 5's "Sympathy for the Devil"
“You were wasted by a teenage mutant ninja angel?”
-Dean to Castiel in season 5’s “Free to Be You and Me"
"Pudding!
-Dean acting crazy in season 5’s “Sam Interrupted"
“Boop!”
-Sam, high on medication in "Sam Interrupted"
Follow the link to the rest:
Slideshow100 Funniest 'Supernatural' Quotes