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"Chronic nicotine administration reversed this hypofrontality, suggesting that administration of nicotine may represent a therapeutic strategy for the treatment of schizophrenia, and a physiological basis for the tendency of patients with schizophrenia to self-medicate by smoking".
Nat Med. 2017 Mar;23(3):347-354. doi: 10.1038/nm.4274. Epub 2017 Jan 23.
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia.
Koukouli F1,2, Rooy M3, Tziotis D4, Sailor KA2,5, O'Neill HC6, Levenga J6, Witte M7, Nilges M4, Changeux JP2, Hoeffer CA6, Stitzel JA6, Gutkin BS3,8, DiGregorio DA2,9, Maskos U1,2.
Author information
1Institut Pasteur, Neurobiologie Intégrative des Systèmes Cholinergiques, Paris, France.2CNRS UMR 3571, Paris, France.3Group for Neural Theory, Laboratoire de Neurosciences Cognitives, INSERM Unité 969, Département d'Études Cognitive, École Normale Supérieure, Paris, France.4Institut Pasteur, Structural Bioinformatics Unit, CNRS UMR 3528, Paris, France.5Institut Pasteur, Perception and Memory Unit, Paris, France.6Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA.7Institute for Neuroanatomy, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Germany.8Centre for Cognition and Decision Making, National Research University Higher School of Economics, Moscow, Russia.9Institut Pasteur, Dynamic Neuronal Imaging Unit, Paris, France.
С учетом ситуации на внутреннем и внешних фронтах - просто-таки необходимо.
"Chronic nicotine administration reversed this hypofrontality, suggesting that administration of nicotine may represent a therapeutic strategy for the treatment of schizophrenia, and a physiological basis for the tendency of patients with schizophrenia to self-medicate by smoking".
Nat Med. 2017 Mar;23(3):347-354. doi: 10.1038/nm.4274. Epub 2017 Jan 23.
Nicotine reverses hypofrontality in animal models of addiction and schizophrenia.
Koukouli F1,2, Rooy M3, Tziotis D4, Sailor KA2,5, O'Neill HC6, Levenga J6, Witte M7, Nilges M4, Changeux JP2, Hoeffer CA6, Stitzel JA6, Gutkin BS3,8, DiGregorio DA2,9, Maskos U1,2.
Author information
1Institut Pasteur, Neurobiologie Intégrative des Systèmes Cholinergiques, Paris, France.2CNRS UMR 3571, Paris, France.3Group for Neural Theory, Laboratoire de Neurosciences Cognitives, INSERM Unité 969, Département d'Études Cognitive, École Normale Supérieure, Paris, France.4Institut Pasteur, Structural Bioinformatics Unit, CNRS UMR 3528, Paris, France.5Institut Pasteur, Perception and Memory Unit, Paris, France.6Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA.7Institute for Neuroanatomy, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Germany.8Centre for Cognition and Decision Making, National Research University Higher School of Economics, Moscow, Russia.9Institut Pasteur, Dynamic Neuronal Imaging Unit, Paris, France.
С учетом ситуации на внутреннем и внешних фронтах - просто-таки необходимо.