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Feb 11, 2005 01:04


The chemical compound potassium chloride (KCl) is a metal halide composed of potassium and chlorine. In a pure state it is odorless, with a white to colorless vitreous crystal, with a face-centred cubic structure that cleaves easily in three directions. KCl is used in medicine, scientific applications, food processing and in judicial execution through lethal injection. It occurs naturally as the mineral sylvite and in combination with sodium chloride as sylvinite.

The majority of the potassium chloride produced is used for making fertilizer[2], since the growth of many plants is limited by their potassium intake. As a chemical feedstock it is used for the manufacture of potassium hydroxide and potassium metal. It is also used in medicine, scientific applications, food processing and in judicial execution through lethal injection.

Potassium is vital in the human body and oral potassium chloride is the common means to replenish it, although it can also be diluted and given intravenously. Medically it is used in the treatment of hypokalemia and associated conditions, for digitalis poisoning, and as an electrolyte replenisher. Side effects can include gastrointestinal discomfort including nausea and vomiting, diarrhea and bleeding of the gut. Overdoses cause hyperkalemia which can lead to paresthesia, cardiac conduction blocks, fibrillation and arrhythmias, also sclerotic effects.

Orally it is toxic, but the LD50 is around 2500 mg/kg. Intravenously this is reduced to just over 100 mg/kg but of more concern are its severe effects on cardiac muscles; high doses can cause cardiac arrest and rapid death.
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