Driving along Oregon and California coast

[allita78]

I'll be driving from Portland, Oregon to San Francisco on Highway 101 next month, and wondering if anyone can recommend some must-see places along the way (I already have the dunes, sea lion caves, redwoods, and a couple of other things on the list).

I'm interested in nature, hiking, and some interesting cultural sites (old shipping ports, for example). I want to avoid crowds and really touristy places, but  hopefully it shouldn't be a problem, since I will be driving during a work week.

Also, what are some good campgrounds along the way? 
Good = spaced-out sites, no RVs, and hopefully nice views :)

Thanks!