Telemarketing
If they inconvenience me one iota, I couldn't care less in the slightest if every last person there lost their job.
You know what else is an inconvenience? When the cops stop me from stealing cars. Someone needs to put a stop to that, and I couldn't care less if every one of those damn, dirty cops lost their jobs, because they're inconveniencing me.
The point being that just because you're inconvenienced doesn't mean jack. The cops are right to arrest criminals and the telemarketers are right to use the phone service they pay for.
They choose to call me, they choose to inconvenience me
You agrees to allow them to call you when you subscribed to a service, the phone service, that explicitly allowed incoming calls from anyone. If you don't want incoming calls from anyone, then you need to find a better phone service. But don't take it out on the telemarketers that they're using the system you subscribe to as per the agreements everyone made.
What if these were ignorant asshats sending 50 million spam messages a day? Would shutting them down be bad because its going to put some people out of work?
No, it would be bad because they paid for their internet access just like everyone else, and so they have the same right to use it as per their agreement with their ISP. If they break that agreement or steal internet access, that's something different entirely and has nothing to do with the spam, but so long as they are completely following their agreement they should be left alone.
If you make the decision to accept email or phone calls from strangers don't complain when you get some.