Nov 12, 2008 00:38
i reread my grad school admissions essay describing my scientific interests. It was horrifying. i thought maybe i should pen a new interest statement (concisely) so I could spit it out later, and to set the record straight in my head. before it was like "I will use synthetic biology to make new complex constructs that will be used in research" which, I'm afraid, means nothing. That's kind of like saying "I will use parts from a clock to make a new clock which I will use as a clock" . haha yale has beaten the synthetic biology out of my head. so now it would look a little different.
Cells "make decisions" that are uncannily intelligent (for example: precisely sorting different cellular "cargo" into different transport "packages") based on biochemical events that are inherently random (for example: any chemical reaction). How do cells utilize, minimize, or exploit this randomness, or biological "noise", to regulate and enforce intelligent decision making? In addition to traditional biochemical and biophysical analyses, I will use new high-resolution imaging techniques to study the molecular basis for these phenomena in vivo by direct visualization.