meh. boring rambling
hmmm. revising. confounded. taking a short break to go and look up SIGN/NICE guidelines to cure what ails me. which is, you know, general stupidity. I'm currently revising work from second year, so I'm not sure how I've never overcome this particular bit of confusion before now...
It's possible that I'm just making up problems for myself :D
I'm sure I am, actually. Or just being a bit stupid. I am revising medical treatment of stable angina, and one of the first line therapies is a beta blocker. lovely. but my problem is that surely this is contraindicated in a fair number of people who have claudication? I don't know, really. I was assuming that most people with claudication will probably have some degree of angina, but I am possibly lying. a lot.
am now side tracked again and looking up incidences of angina and intermittent claudication on pubmed. I love pubmed. Feels a little bit like going to the pub, until you get there. in that it is a search engine. and they don't generally serve gin.
oh, bloody hell. maybe they don't occur together all that often. When the Framingham study isn't helping you, you know you're fucked. Well, I'm fucked, at any rate.
I wonder if beta blockers are even contrad by intermittent claudication? I'm sure they are, though. I'm suuuure they are.
No, I need some SIGN guidelines. they're where it's at, anyway. stupid contrary mary OHCM can twat off.
I love the OHCM really. I do. It's one of my better friends.
Christ, revision turns me into a really weird person.
ho hum. SIGN, good times. Not really answering my question, though. Anyway, after all of that I think I'm going to assume that I'd just give something else instead. And maybe they don't occur together all that often. Anyway. Calcium channel blockers. They're where it's at. and long-acting nitrates, apparently. And nicorandil? I don't even know what that is. oh, apparently it's a potassium channel activator, and it reduces the metabolic demands on the heart whilst increasing myocardial perfusion. bet this has something horrible to do with hyperpolarisation and action potentials, and I might actually have to do some thinking. bollocks. stupid action potentials. at least I can think about Na+/K+ATPases and make ATP jokes in my head. How much does a mitochondrion cost, bbs? THAT'S RIGHT. 80p! ha. I'm the only one who ever laughs.
might get out the pharmacology text book. I'm sure this wasn't so difficult in second year. I mean, it's angina! It's piss easy. I need to do ischaemic heart disease tonight. And hopefully some pathophysiology of valvular heart disease, but fuuuuck, not at this bloody rate.
*sulks*
maybe I need more tea. tea break time! woot woot
It's possible that I'm just making up problems for myself :D
I'm sure I am, actually. Or just being a bit stupid. I am revising medical treatment of stable angina, and one of the first line therapies is a beta blocker. lovely. but my problem is that surely this is contraindicated in a fair number of people who have claudication? I don't know, really. I was assuming that most people with claudication will probably have some degree of angina, but I am possibly lying. a lot.
am now side tracked again and looking up incidences of angina and intermittent claudication on pubmed. I love pubmed. Feels a little bit like going to the pub, until you get there. in that it is a search engine. and they don't generally serve gin.
oh, bloody hell. maybe they don't occur together all that often. When the Framingham study isn't helping you, you know you're fucked. Well, I'm fucked, at any rate.
I wonder if beta blockers are even contrad by intermittent claudication? I'm sure they are, though. I'm suuuure they are.
No, I need some SIGN guidelines. they're where it's at, anyway. stupid contrary mary OHCM can twat off.
I love the OHCM really. I do. It's one of my better friends.
Christ, revision turns me into a really weird person.
ho hum. SIGN, good times. Not really answering my question, though. Anyway, after all of that I think I'm going to assume that I'd just give something else instead. And maybe they don't occur together all that often. Anyway. Calcium channel blockers. They're where it's at. and long-acting nitrates, apparently. And nicorandil? I don't even know what that is. oh, apparently it's a potassium channel activator, and it reduces the metabolic demands on the heart whilst increasing myocardial perfusion. bet this has something horrible to do with hyperpolarisation and action potentials, and I might actually have to do some thinking. bollocks. stupid action potentials. at least I can think about Na+/K+ATPases and make ATP jokes in my head. How much does a mitochondrion cost, bbs? THAT'S RIGHT. 80p! ha. I'm the only one who ever laughs.
might get out the pharmacology text book. I'm sure this wasn't so difficult in second year. I mean, it's angina! It's piss easy. I need to do ischaemic heart disease tonight. And hopefully some pathophysiology of valvular heart disease, but fuuuuck, not at this bloody rate.
*sulks*
maybe I need more tea. tea break time! woot woot