What seems to be the path of most democratic change, is when the liberals infilterate the conservatives and take over the status quo: this often happens later in a movement's maturity or if situations change. In different generations, there are also less animosity and old drama to overcome, neutral parties are more likely to compromise then parties who feel like they are losing and are under attack.
With this in mind: I present you
Health Care. As suggested by businesses, unions, and the AARP (American Association of Retired People).
If politics is like Chess, each new coalition that comes forward is a move. This move might prove interesting. Also manuvering in for the kill is Arnold Schwartzenaiger in California and Mitt Romney in Massachusettes not to mention Howard Dean: all these people made health care a priority. Big corporations who have always provided health care for their more valued employees also most likely feel that rivals that provide less coverage are free riding. Anyway: if this becomes a business investment idea as well as a liberal idea there is very little insurance companies and pharmacutical companies can do. They might be outmanuvered. I think there should definately be a push to encourage new research but there isn't all that much that I have seen that shows companies are all that interested in groundbreaking research these days (outside the stem cell debate) and I agree they should have plenty of incentives for that!!
It seems that sometimes economics is counter-intuitive. You can be doing something you think will help research but if you treat all research the same then you don't get much that spans new fields. I do believe in unintended consequences. :P