:: TMI drug side effects ::
So I was browsing the image site Ffffound! and ran into the following book cover: braininjuredchild.
I know all of those words except for athetoid so I asked my good friend Wikipedia: Athetosis is a continuous stream of slow, sinuous, writhing movements, typically of the hands and feet. Movements typical to athetosis are sometimes called athetoid movements.
So, off to YouTube.com, to look it up: Athetoid tonicity in a hand.
As soon as I saw that, I went "Aha!" because (let's be frank) when I take certain hallucinogens (e.g. psilocybin or orally administered chocolated cannabis extracts AKA 'eatables' or 'edibles') I have a tendency to do motions just like that and I've always wondered why.
Here's why (emphasis mine):
Combined histochemical and biochemical analysis revealed that psilocybin (5-50 mg/kg i.p.) and dimethyltryptamine (40-200 mg/kg i.p.) reduced the 5-hydroxytryptamine (5-HT) depletion in the brain and the spinal cord after amine synthesis inhibition, indicating reduced 5-HT turnover. This effect was not due to monoamine oxidase inhibition. The turnover of norepinephrine in the central nervous system was somewhat accelerated after the higher doses of psilocybin and dimethyltryptamine. In experiments on rat hindlimb reflexes, psilocybin (1-50 mg/kg i.p.) and N, N-dimethyltryptamine (10-50 mg/kg i.p.) caused changes similar to those seen after treatment with the 5-HT precursor 5-hydroxytryptophan, i.e., hyperextensions and athetoid movements...
From HALLUCINOGENIC DRUGS OF THE INDOLEALKYLAMINE TYPE AND CENTRAL MONOAMINE NEURONS here
Ta-da! THE MORE YOU KNOW. So the feeling like I'm spiralling with the universe? It actually has a cause.
Now if I could just figure out where/why it retards/suppresses the vocal speech center of my brain, then I'd be in business. For some reason, I can still understand speech, but it becomes extremely difficult for me to speak out myself. Anyone have the research?
I know all of those words except for athetoid so I asked my good friend Wikipedia: Athetosis is a continuous stream of slow, sinuous, writhing movements, typically of the hands and feet. Movements typical to athetosis are sometimes called athetoid movements.
So, off to YouTube.com, to look it up: Athetoid tonicity in a hand.
As soon as I saw that, I went "Aha!" because (let's be frank) when I take certain hallucinogens (e.g. psilocybin or orally administered chocolated cannabis extracts AKA 'eatables' or 'edibles') I have a tendency to do motions just like that and I've always wondered why.
Here's why (emphasis mine):
Combined histochemical and biochemical analysis revealed that psilocybin (5-50 mg/kg i.p.) and dimethyltryptamine (40-200 mg/kg i.p.) reduced the 5-hydroxytryptamine (5-HT) depletion in the brain and the spinal cord after amine synthesis inhibition, indicating reduced 5-HT turnover. This effect was not due to monoamine oxidase inhibition. The turnover of norepinephrine in the central nervous system was somewhat accelerated after the higher doses of psilocybin and dimethyltryptamine. In experiments on rat hindlimb reflexes, psilocybin (1-50 mg/kg i.p.) and N, N-dimethyltryptamine (10-50 mg/kg i.p.) caused changes similar to those seen after treatment with the 5-HT precursor 5-hydroxytryptophan, i.e., hyperextensions and athetoid movements...
From HALLUCINOGENIC DRUGS OF THE INDOLEALKYLAMINE TYPE AND CENTRAL MONOAMINE NEURONS here
Ta-da! THE MORE YOU KNOW. So the feeling like I'm spiralling with the universe? It actually has a cause.
Now if I could just figure out where/why it retards/suppresses the vocal speech center of my brain, then I'd be in business. For some reason, I can still understand speech, but it becomes extremely difficult for me to speak out myself. Anyone have the research?