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atomic_joe2 January 11 2012, 09:43:03 UTC
It's evolution, baby. I remember seeing a Richard Dawkins programme about two prostitutes in Kenya who had developed an immunity to HIV. Its what happens.

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pluckygirl January 11 2012, 11:26:51 UTC
How did that happen?

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dncingmalkavian January 11 2012, 15:25:09 UTC
Nature does that sometimes.

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entropius January 11 2012, 18:12:04 UTC
Some people are just naturally resistant to HIV; there's a mutation that makes the virus have extreme difficulty invading their cells. There's actually a case of an accidental AIDS "cure" -- somebody got a bone marrow transplant from a donor who was resistant, and the transplanted immune system was resistant to HIV.

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benndragon January 11 2012, 17:38:21 UTC
Was anything mentioned about the mechanism of that immunity, or are we still trying to figure that out? (Because that's some pretty important info right there)

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serendipity_15 January 11 2012, 18:11:14 UTC
My med school friend was telling me about the CCR 5 protein rceptor present and how people with two copies of Delta-32 mutation, which deletes a portion of the CCR5 gene, are resistant to macrophage strains of HIV-1 infection.

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