Five. Firefly: Mal & River.
"You know what the first rule of flying is?...Love. You can learn all the math in the 'verse...But you take a boat in the air that you don't love...She'll shake you off just as sure as the turn of the worlds. Love keeps her in the air when she ought to fall down...
Tells you she's hurting before she keels. Makes her a home."
-Mal Reynolds
Four. Sanctuary: Henry & Ashley.
"Hey, making Ashley crazy-mad is not in the same category as disabling her."
-Henry Foss
Three. Supernatural: Castiel & Anna.
"I don't know what to do. Please tell me what to do."
-Castiel
Two. Doctor Who: Nine & Rose.
"I could save the world but lose you.
-The Doctor
One. Battlestar Galactica: Kara & Leoben.
"We've tried to be patient about your model's obsession with this woman. Playing house with her on New Caprica was one thing."
-Natalie (Number Six model)