If you're a fandom type, or even if you're not, go check out
Sweet Charity.
To quote from the FAQ:
This is a charity auction, selling the (wicked mad) fannish skillz of Charity Hos for cold hard donations. You can buy, okay rent, the talents of vidders, writers, artists, costumer, jewelers, baker and wow so much more and they will create goodies just for you, to your specs.
I'm going to be putting up cookies, homebaked bread, and a plushie (and maybe more, if I think I can handle it), and the Demon Fart Cabbage group may be adding a print or two.
It runs twice a year, in March and September. For this run, sign ups for selling are open until September 28, and bidding is from September 29 - October 4.
EDIT: I totally forgot to say which charity it's for. This September auction is for
Invisible Children, a charity that is dedicated to helping victims of the war in Uganda. It is aimed at stopping the war, as well as providing aid, education, and leadership skills to the new generation of Ugandans.