CHRONIC FATIGUE EXTRAVAGANZA
Dear Dr. Zapomatic,
I have an appointment with you soooon. I have been wanting to compile a summary of interesting or unique symptoms or observations, in my CFS, which might be of interest and use to you and other professionals. However, I have as yet been unable to compile this. In the meantime, I do have a few links which may or may not be useful to you. I thought I would add these links to an online post for others, and so, the links of most salience for you shall be in BOLD for your convenience. You need not investigate the other links unless you wish to. This list will also be sent as an attachment if I can manage it w/ my email.
PS - I am hearing you on the radio constantly, with 4-5 different bits on the Zika virus! That is an excellent way to keep me reminded of my appointment. (Speaking of mosquitoes - ANYTHING which causes inflammation, provokes my CFS 'relapses', from mosquito bites, to a gum infection, to poison ivy(!), to colds/flu, to what feels to be brain inflammation).
- madman101, Esquire
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
What is Chronic Fatigue Syndrome, and its related conditions like FMS, GWS, MCS/EI, PPFS, (and maybe even diabetes and Alzheimers?!)? Here is a tiny intro...
What Are:
Chronic Fatigue Syndrome (aka CFS, ME, CFIDS),
Fibromyalgia (aka Fibro, FM, FMS),
Chemical Sensitivity (aka CS, MCS, EI)
The whole point of this post was to find for you, dear reader, a book review which I found in my copy of the Canary Times. I did not find it online, and I haven't gotten re-setup with scanning. That will prolly happen soon. If you want5 to find the same book review, which I doubt that any of you will cuz uh, then you can write to the Canary Times, (Volume 13, No. 1, April 2016). (Book Review: Prostituting Science). Do it if you care, its a good newsletter, free if you're pathetic like me.
* The Canary Times
WHAT IS MYALGIC ENCEPHALOMYELITIS? ("CHRONIC FATIGUE SYNDROME")
Myalgic Encephalomyelitis (ME) is a systemic neuroimmune condition characterized by post-exertional malaise (a severe worsening of symptoms after even minimal exertion). It causes dysregulation of both the immune system and the nervous system. The effects of ME are devastating enough to leave 25% of patients housebound or bedbound. For moderate to severe patients, living with ME is like living with late-stage cancer, advanced stage AIDS, or congestive heart failure for decades.
Chronic Fatigue Syndrome: NJ Woman Suffers From Unheard Of, Debilitating Disease, Creates 'Canary In A Coal Mine' Documentary
Jennifer Brea was at a restaurant when she experienced a sudden, severe wave of brain fog, and was unable to read the menu - it was like the letters were in a different language. Shortly after this episode, she was afflicted with incapacitating fatigue, part of a debilitating disease that not many people, or even doctors, have heard of - myalgic encephalomyelitis (ME), more commonly known as chronic fatigue syndrome (CFS). Doctors don’t know what causes it, how to cure it, or even how to treat it.
"CANARY IN A COAL MINE": A documentary film about the world's most prevalent orphan disease
WBUR, Listen live The New Science Of Exhaustion
As many as two and a half million Americans suffer from chronic fatigue syndrome. There is no formal diagnosis - but there is a huge debate about what it is and what to call it. Many who suffer from it say the name, chronic fatigue syndrome, trivializes the illness. So now, the Institute of Medicine has come up with a new diagnosis, and a new name: Systemic Exertion Intolerance Disease, to better describe its debilitating effects. This hour, On Point: what’s in a name? The debate over chronic fatigue syndrome.
* Researchers find herpes strain in the nervous system
There are a couple strains of herpes so common that researchers estimate 90% of the human population have them. These strains, human herpes 6 and human herpes 7, usually do not cause severe symptoms when people acquire them. But researchers know that under certain circumstances, dormant herpes viruses in the body can unexpectedly come roaring back and cause complications not typically associated with herpes virus.
* Stiff arteries linked with memory problems, mouse study suggests
Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings may eventually reveal how arterial stiffness leads to Alzheimer’s and other diseases involving dementia.
Cerebrovascular disease linked to Alzheimer's: Study finds association between diseases in brain blood vessels and dementia
While strokes are known to increase risk for dementia, much less is known about diseases of large and small blood vessels in the brain, separate from stroke, and how they relate to dementia. Diseased blood vessels in the brain itself, which commonly is found in elderly people, may contribute more significantly to Alzheimer's disease dementia than was previously believed, according to new study results published in June in The Lancet Neurology, a British medical journal... "Cerebral vessel pathology might be an under-recognized risk factor for Alzheimer's disease dementia," the researchers wrote.
* Binswanger's disease - Similar to my experience, except mine seems to involve immune/inflammation + lower brain/spinal fluid + low brain BP.
* Analogy: Post-stroke shifts in gut bacteria could cause additional brain injury
* * Hope for Chronic Fatigue Syndrome: The debate over this mysterious disease is suddenly shifting. - (rebuking the PACE study)
'CFS IS a real condition': People with the debilitating illness have 'telltale signs in their blood' - * see STUDY below * ------------
- Critics have argued the condition, also called ME, is all in the mind
- Symptoms include extreme physical and mental fatigue and painful limbs
- Study: These people have specific chemical signature in their blood
- Bizarrely, the changes echo those seen in hibernating animals
*** STUDY: Robert K. Naviaux, MD, PhD, et al ---------
** Watch as GcMAF Treatment Kills Cancer Cells in Real Time
"Besides cancer, the conditions listed as appropriate candidates for GcMAF treatment include":
Autoimmune diseases
Epstein-Barr Virus (EBV)
Hepatitis B virus (HBV)
Herpes Simplex virus (HSV)
Cystitis
Hepatitis C virus (HCV)
Multiple sclerosis (MS)
Urinary tract infection (UTI)
Autism Spectrum Disorders (ASD)
Rheumatoid arthritis (RA)
Endometriosis
Chronic Fatigue Syndrome (CFS)
Lyme disease (Lyme borreliosis)
IgA deficiency disorder
Myalgic Encephalomyelitis (ME)
Mycobacteria infections
Parkinson’s disease
Tuberculosis
Fibromyalgia
Human papillomavirus (HPV)
Lupus (Systemic lupus erythematosus, SLE)
HIV AIDS
Dengue fever
Pneumonia infection
Warts caused by viral infection
Norovirus
Malaria Influenza virus (flu)
Herpes simplex virus (HSV)
Q fever (Coxiella burnetii)
Polycystic ovary syndrome (PCOS)
Chicken pox (varicella zoster virus)
Psoriasis
Respiratory tract infections
Ulcerative colitis, Crohn’s disease
Type 1 diabetes (T1DM), insulin-dependent diabetes (IDDM)
Type 1.5 diabetes, Latent autoimmune diabetes of adults (LADA)
------------------------------An earlier post:
I was trying to find out if Illinois allows medical marijuana for CFS. I still don't know. But here is a good article describing CFS. One good thing about this article is that it emphasises that stress is a major CFS trigger, and that stress-management should be an important therapy. It also notes that medical marijuana is used to help symptoms. One bad thing is that it singles out Epstein Barr virus somewhat, which is improper. EBV my only be a symptom. People w/ CMV, or other Herpes viruses, can have CFS which is just as valid as those w/ EBV. (Note: I need to study Herpes viruses - as I recently heard they are classified as "double-strand DNA" viruses, which is interesting to me).
*** Medical Marijuana Treatments for CFS
Another good article, for the person who might have CFS: What is CFS?
From the first article:
Cannabinoids Help Relieve CFS Symptoms
1. Relief from headaches
2. anti-depression
3. anti-inflammatory
4. heighten focus
5. muscle pain
6. support immune system
7. improve energy level
Best Strains: Sativa hybrid, Sativa x Indica, Sativa dominant hybrid.
East Coast Sour Diesel, Jack Herer, Sweet Blu
-----------------------------------An earlier post:
NOTE: An important HPA and RETICULAR / ACh / "gating" researcher is : JAY GOLDSTEIN.
The hypothalamic-pituitary-adrenal axis is a complex set of interactions between the hypothalamus (a part of the brain), the pituitary gland (also part of the brain) and the adrenal or supradrenal glands (at the top of each kidney.) The HPA axis helps regulate things such as your temperature, digestion, immune system, mood, sexuality and energy usage. It's also a major part of the system that controls your reaction to stress, trauma and injury.
Research links fibromyalgia and chronic fatigue syndrome with abnormalities in genes involved in the HPA axis. (Primarily the hypothalamus in fibromyalgia and primarily the adrenals in chronic fatigue syndrome.)...
* The HPA axis also is involved in anxiety disorder, bipolar disorder, post-traumatic stress disorder, clinical depression, burnout and irritable bowel syndrome.
* "National CFIDS Foundation's Research Finds Chromosome Damage in Patients Diagnosed with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis." - & - "Neurotoxin Discovered in Chronic Fatigue Syndrome" (ciguatera)
Ciguatera | Soursop
Welcome to ChronicNeurotoxins, Inc. Home Page
* A Simple Explanation of the Glutathione/Methylation Depletion Theory of ME/CFS by Rich Von Konynenburg
Symptoms would include: disturbed sense of co-ordination, paraesthesiae, loss of memory, abnormal reflexes, weakness, loss of muscle strength, exhaustion, confusion, low self-confidence, spacticity, incontinence, impaired vision, abnormal gait, frequent need to pass water and psychological deviances. Non-anaemic deficiencies play a role in diseases such as Multiple Sclerosis, Fibromyalgia, Diabetes and Chronic Fatigue Syndrome. Schizophrenia has also been successfully treated with B12 plus other supplements, and cardiovascular disease is linked to B12 deficiency while herpes zoster used to be treated with B12 injections back in the 1950s. - An Introduction To Cobalamin Metabolism
* Chronic Fatigue and Nutrition: Autism and DAN Gone Wrong
Changing Your Gut Flora Pt I: Food to Feed the Good Bacteria in Chronic Fatigue Syndrome
----------------------------------------
Protecting your gut flora could help prevent type 1 diabetes
*** Chronic fatigue syndrome is in your gut, not your head
Physicians have been mystified by chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn't alleviated by rest. There are no known triggers, and diagnosis requires lengthy tests administered by an expert.
Now, for the first time, Cornell University researchers report they have identified biological markers of the disease in gut bacteria and inflammatory microbial agents in the blood.
New Research Discovers That Depression Is An Allergic Reaction To Inflammation
FEELguide - New research is revealing that many cases of depression are caused by an allergic reaction to inflammation. Tim de Chant of NOVA writes: “Inflammation is our immune system’s natural response to injuries, infections, or foreign compounds. When triggered, the body pumps various cells and proteins to the site through the blood stream, including cytokines, a class of proteins that facilitate intercellular communication. It also happens that people suffering from depression are loaded with cytokines.” Inflammation is caused by obesity, high sugar diets, high quantities of trans fats, unhealthy diets in general, and other causes. By treating the inflammatory symptoms of depression - rather than the neurological ones - researchers and doctors are opening up an exciting new dimension in the fight against what has become a global epidemic. Caroline Williams of The Guardian writes: “The good news is that the few clinical trials done so far have found that adding anti-inflammatory medicines to antidepressants not only improves symptoms, it also increases the proportion of people who respond to treatment, although more trials will be needed to confirm this. There is also some evidence that omega 3 and curcumin, an extract of the spice turmeric, might have similar effects.
I have an appointment with you soooon. I have been wanting to compile a summary of interesting or unique symptoms or observations, in my CFS, which might be of interest and use to you and other professionals. However, I have as yet been unable to compile this. In the meantime, I do have a few links which may or may not be useful to you. I thought I would add these links to an online post for others, and so, the links of most salience for you shall be in BOLD for your convenience. You need not investigate the other links unless you wish to. This list will also be sent as an attachment if I can manage it w/ my email.
PS - I am hearing you on the radio constantly, with 4-5 different bits on the Zika virus! That is an excellent way to keep me reminded of my appointment. (Speaking of mosquitoes - ANYTHING which causes inflammation, provokes my CFS 'relapses', from mosquito bites, to a gum infection, to poison ivy(!), to colds/flu, to what feels to be brain inflammation).
- madman101, Esquire
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
What is Chronic Fatigue Syndrome, and its related conditions like FMS, GWS, MCS/EI, PPFS, (and maybe even diabetes and Alzheimers?!)? Here is a tiny intro...
What Are:
Chronic Fatigue Syndrome (aka CFS, ME, CFIDS),
Fibromyalgia (aka Fibro, FM, FMS),
Chemical Sensitivity (aka CS, MCS, EI)
The whole point of this post was to find for you, dear reader, a book review which I found in my copy of the Canary Times. I did not find it online, and I haven't gotten re-setup with scanning. That will prolly happen soon. If you want5 to find the same book review, which I doubt that any of you will cuz uh, then you can write to the Canary Times, (Volume 13, No. 1, April 2016). (Book Review: Prostituting Science). Do it if you care, its a good newsletter, free if you're pathetic like me.
* The Canary Times
WHAT IS MYALGIC ENCEPHALOMYELITIS? ("CHRONIC FATIGUE SYNDROME")
Myalgic Encephalomyelitis (ME) is a systemic neuroimmune condition characterized by post-exertional malaise (a severe worsening of symptoms after even minimal exertion). It causes dysregulation of both the immune system and the nervous system. The effects of ME are devastating enough to leave 25% of patients housebound or bedbound. For moderate to severe patients, living with ME is like living with late-stage cancer, advanced stage AIDS, or congestive heart failure for decades.
Chronic Fatigue Syndrome: NJ Woman Suffers From Unheard Of, Debilitating Disease, Creates 'Canary In A Coal Mine' Documentary
Jennifer Brea was at a restaurant when she experienced a sudden, severe wave of brain fog, and was unable to read the menu - it was like the letters were in a different language. Shortly after this episode, she was afflicted with incapacitating fatigue, part of a debilitating disease that not many people, or even doctors, have heard of - myalgic encephalomyelitis (ME), more commonly known as chronic fatigue syndrome (CFS). Doctors don’t know what causes it, how to cure it, or even how to treat it.
"CANARY IN A COAL MINE": A documentary film about the world's most prevalent orphan disease
WBUR, Listen live The New Science Of Exhaustion
As many as two and a half million Americans suffer from chronic fatigue syndrome. There is no formal diagnosis - but there is a huge debate about what it is and what to call it. Many who suffer from it say the name, chronic fatigue syndrome, trivializes the illness. So now, the Institute of Medicine has come up with a new diagnosis, and a new name: Systemic Exertion Intolerance Disease, to better describe its debilitating effects. This hour, On Point: what’s in a name? The debate over chronic fatigue syndrome.
* Researchers find herpes strain in the nervous system
There are a couple strains of herpes so common that researchers estimate 90% of the human population have them. These strains, human herpes 6 and human herpes 7, usually do not cause severe symptoms when people acquire them. But researchers know that under certain circumstances, dormant herpes viruses in the body can unexpectedly come roaring back and cause complications not typically associated with herpes virus.
* Stiff arteries linked with memory problems, mouse study suggests
Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings may eventually reveal how arterial stiffness leads to Alzheimer’s and other diseases involving dementia.
Cerebrovascular disease linked to Alzheimer's: Study finds association between diseases in brain blood vessels and dementia
While strokes are known to increase risk for dementia, much less is known about diseases of large and small blood vessels in the brain, separate from stroke, and how they relate to dementia. Diseased blood vessels in the brain itself, which commonly is found in elderly people, may contribute more significantly to Alzheimer's disease dementia than was previously believed, according to new study results published in June in The Lancet Neurology, a British medical journal... "Cerebral vessel pathology might be an under-recognized risk factor for Alzheimer's disease dementia," the researchers wrote.
* Binswanger's disease - Similar to my experience, except mine seems to involve immune/inflammation + lower brain/spinal fluid + low brain BP.
* Analogy: Post-stroke shifts in gut bacteria could cause additional brain injury
* * Hope for Chronic Fatigue Syndrome: The debate over this mysterious disease is suddenly shifting. - (rebuking the PACE study)
'CFS IS a real condition': People with the debilitating illness have 'telltale signs in their blood' - * see STUDY below * ------------
- Critics have argued the condition, also called ME, is all in the mind
- Symptoms include extreme physical and mental fatigue and painful limbs
- Study: These people have specific chemical signature in their blood
- Bizarrely, the changes echo those seen in hibernating animals
*** STUDY: Robert K. Naviaux, MD, PhD, et al ---------
** Watch as GcMAF Treatment Kills Cancer Cells in Real Time
"Besides cancer, the conditions listed as appropriate candidates for GcMAF treatment include":
Autoimmune diseases
Epstein-Barr Virus (EBV)
Hepatitis B virus (HBV)
Herpes Simplex virus (HSV)
Cystitis
Hepatitis C virus (HCV)
Multiple sclerosis (MS)
Urinary tract infection (UTI)
Autism Spectrum Disorders (ASD)
Rheumatoid arthritis (RA)
Endometriosis
Chronic Fatigue Syndrome (CFS)
Lyme disease (Lyme borreliosis)
IgA deficiency disorder
Myalgic Encephalomyelitis (ME)
Mycobacteria infections
Parkinson’s disease
Tuberculosis
Fibromyalgia
Human papillomavirus (HPV)
Lupus (Systemic lupus erythematosus, SLE)
HIV AIDS
Dengue fever
Pneumonia infection
Warts caused by viral infection
Norovirus
Malaria Influenza virus (flu)
Herpes simplex virus (HSV)
Q fever (Coxiella burnetii)
Polycystic ovary syndrome (PCOS)
Chicken pox (varicella zoster virus)
Psoriasis
Respiratory tract infections
Ulcerative colitis, Crohn’s disease
Type 1 diabetes (T1DM), insulin-dependent diabetes (IDDM)
Type 1.5 diabetes, Latent autoimmune diabetes of adults (LADA)
------------------------------An earlier post:
I was trying to find out if Illinois allows medical marijuana for CFS. I still don't know. But here is a good article describing CFS. One good thing about this article is that it emphasises that stress is a major CFS trigger, and that stress-management should be an important therapy. It also notes that medical marijuana is used to help symptoms. One bad thing is that it singles out Epstein Barr virus somewhat, which is improper. EBV my only be a symptom. People w/ CMV, or other Herpes viruses, can have CFS which is just as valid as those w/ EBV. (Note: I need to study Herpes viruses - as I recently heard they are classified as "double-strand DNA" viruses, which is interesting to me).
*** Medical Marijuana Treatments for CFS
Another good article, for the person who might have CFS: What is CFS?
From the first article:
Cannabinoids Help Relieve CFS Symptoms
1. Relief from headaches
2. anti-depression
3. anti-inflammatory
4. heighten focus
5. muscle pain
6. support immune system
7. improve energy level
Best Strains: Sativa hybrid, Sativa x Indica, Sativa dominant hybrid.
East Coast Sour Diesel, Jack Herer, Sweet Blu
-----------------------------------An earlier post:
NOTE: An important HPA and RETICULAR / ACh / "gating" researcher is : JAY GOLDSTEIN.
The hypothalamic-pituitary-adrenal axis is a complex set of interactions between the hypothalamus (a part of the brain), the pituitary gland (also part of the brain) and the adrenal or supradrenal glands (at the top of each kidney.) The HPA axis helps regulate things such as your temperature, digestion, immune system, mood, sexuality and energy usage. It's also a major part of the system that controls your reaction to stress, trauma and injury.
Research links fibromyalgia and chronic fatigue syndrome with abnormalities in genes involved in the HPA axis. (Primarily the hypothalamus in fibromyalgia and primarily the adrenals in chronic fatigue syndrome.)...
* The HPA axis also is involved in anxiety disorder, bipolar disorder, post-traumatic stress disorder, clinical depression, burnout and irritable bowel syndrome.
* "National CFIDS Foundation's Research Finds Chromosome Damage in Patients Diagnosed with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis." - & - "Neurotoxin Discovered in Chronic Fatigue Syndrome" (ciguatera)
Ciguatera | Soursop
Welcome to ChronicNeurotoxins, Inc. Home Page
* A Simple Explanation of the Glutathione/Methylation Depletion Theory of ME/CFS by Rich Von Konynenburg
Symptoms would include: disturbed sense of co-ordination, paraesthesiae, loss of memory, abnormal reflexes, weakness, loss of muscle strength, exhaustion, confusion, low self-confidence, spacticity, incontinence, impaired vision, abnormal gait, frequent need to pass water and psychological deviances. Non-anaemic deficiencies play a role in diseases such as Multiple Sclerosis, Fibromyalgia, Diabetes and Chronic Fatigue Syndrome. Schizophrenia has also been successfully treated with B12 plus other supplements, and cardiovascular disease is linked to B12 deficiency while herpes zoster used to be treated with B12 injections back in the 1950s. - An Introduction To Cobalamin Metabolism
* Chronic Fatigue and Nutrition: Autism and DAN Gone Wrong
Changing Your Gut Flora Pt I: Food to Feed the Good Bacteria in Chronic Fatigue Syndrome
----------------------------------------
Protecting your gut flora could help prevent type 1 diabetes
*** Chronic fatigue syndrome is in your gut, not your head
Physicians have been mystified by chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn't alleviated by rest. There are no known triggers, and diagnosis requires lengthy tests administered by an expert.
Now, for the first time, Cornell University researchers report they have identified biological markers of the disease in gut bacteria and inflammatory microbial agents in the blood.
New Research Discovers That Depression Is An Allergic Reaction To Inflammation
FEELguide - New research is revealing that many cases of depression are caused by an allergic reaction to inflammation. Tim de Chant of NOVA writes: “Inflammation is our immune system’s natural response to injuries, infections, or foreign compounds. When triggered, the body pumps various cells and proteins to the site through the blood stream, including cytokines, a class of proteins that facilitate intercellular communication. It also happens that people suffering from depression are loaded with cytokines.” Inflammation is caused by obesity, high sugar diets, high quantities of trans fats, unhealthy diets in general, and other causes. By treating the inflammatory symptoms of depression - rather than the neurological ones - researchers and doctors are opening up an exciting new dimension in the fight against what has become a global epidemic. Caroline Williams of The Guardian writes: “The good news is that the few clinical trials done so far have found that adding anti-inflammatory medicines to antidepressants not only improves symptoms, it also increases the proportion of people who respond to treatment, although more trials will be needed to confirm this. There is also some evidence that omega 3 and curcumin, an extract of the spice turmeric, might have similar effects.