At work this week, I had to build emergency pong playing robots. We're all throwing stuff together for some last minute demos and that was my assignment.
Moving your home directory to a new partition isn't as easy in Windows as it is in Os X. And it isn't as easy in Os X as it is in most Unixes.
NTFS might be the new lowest-common-denominator file system. It works out of the box on my Linux box and with MacFUSE under Os X. Apparently there's some issue that makes this a bit slow, though.
I'm about to start encrypting my data wholesale. I think I'll probably start using TrueCrypt. People who know more than me about this stuff should give me advice.