You can, in fact, retrain your brain to focus on the positive sides of trying something-you know, like This is a thing that I want, that might make me really happy-instead of sabotaging yourself with negative thoughts. Self-sabotage involves a lot of self-talk (“What’s the point, everyone will just think I’m lame”); you need to counter that with a new kind of self-talk that’s about how great you are (“Oh man, it’s gonna be so cool when I can shred on that guitar”). J wrote a post right after Thanksgiving talking about watching his parents walk down the sidewalk and head home, and how at that moment struck him in the realization that one day one or both of them would be gone from our lives. Yes, its encouragement to hold fast to the ones you love, but for me its also an encouragement not to waste the time you have. I know, I talk about this a lot, but it really is something that's always on my mind. To me, there is no point in living if you aren't willing to take risks. Sell your art, participate in open mic night, host a party, try a new food. There is no better day than today, one day you'll be too old, or too sick, or too whatever to take a risk and try something new.