YOU KNOW FOR A FACT DEAN WOULD TRY TO PICK UP A 19TH CENTURY HOOKER. And then Sam would be all, "Dean...they probably aren't clean," and slowly manage to get Dean back on track. Meanwhile Holmes would be kicking ass not giving a shit because Holmes doesn't need the opposite sex and Watson would be all, "Sam and Dean?"
Let's blend a little 2009 movie in and say Moriarty kidnaps Irene to lure Holmes into whatever trap he's set, and just happens upon Cas, who is a strange man in a suit and trenchcoat. Moriarty is going to wrap that shit up.
SERIOUSLY I'VE GOT LIKE A LITTLE PLOT AND SHIT FIGURED OUT FOR THIS. And a cover but I need to scan it in and I'm so lazy so you get Irene and Cas.
Later I'll post the doodles I've got on paper and stuff that I've done throughout the day.
(psh irene would say that but you know in the back of her mind she's got a plan in motion. irene is ready for anything.)