i got this from the fox forum and suddenly i want to watch this episode so badly!
In act your age, House gives Wilson tickets to a play(Why does House have tickets to a play???). He takes Cuddy. The next day House is all Cuddy, why do you have extra concealer on? What did u do last night and cuddy says she went to a play... House confronts Wilson saying you only ask a girl to a play if you want to see her naked. House then messes with him to make him think that Cuddy has the hots for him, i.e. sends Wilson flowers and signs the card "lisa." meanwhile. Wilson is messing with House repeatedly saying he slept with Cuddy, which stuns House each time. At the end, House tells Cuddy he has tickets to a play and invites her.
(I think that House is afraid that Wilson and Cuddy get together for real that A: He won't be able to get away with stuff because Wilson might go tell on him to Cuddy. B: That he will lose his best friend, because Wilson will spending all his free time with Cuddy. I just don't see the House/Cuddy think because he NEVER shows her any respect.)