So, if you romanced Liara in Mass Effect 1, romanced a different squad-mate in Mass Effect 2, complete the suicide mission before doing LotSB, then do certain Paragon interrupts during LotSB, Liara gets, well, a little upset.
Let's say you romanced Miss Lawson and her low-cut jumpsuit in ME2....
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MEOW! (I love it when she rolls her eyes on "Miss Lawson")
Or maybe Garrus is calibrating more than the Normandy's guns with your FemShep....
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Or is FemShep more interested in seeing Jacob with his shirt off....
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Or trying to take the place of a dying man's wife....
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Liara also accuses Shepard of trying to get under Tali's mask and tossing her aside for a tattooed woman with anger issues!
That's one of the things I love about Mass Effect 2, no matter how many times you've played the game, it's always a little bit different.
Only eight more months.