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Chemical data \nFormula C22H19N3O4 \n\n6 Trivia \nSide effects\nTrivia\n\nThe empirical formula for tadalafil is C22H19N3O4, and its official organic name is (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a- hexahydro-2-methyl-pyrazino[1 ,2 :1,6]pyrido[3,4-b]indole-1,4-dione. The molecular weight is 389.41. The tablets are yellow, film-coated, and almond-shaped, and are produced in 5, 10, or 20mg doses.\nATC code G04BE08 \n7 External links \n\n \nSince people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (GTN Spray), these patients should seek immediate medical attention if they experience anginal chest pain [1]. In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.\n[edit]\nMol. weight 389.404 g/mol \nSome individuals with the surname of "Cialis" objected to the naming of Lilly's drug, but the pharmaceutical giant insists that the drug's name has nothing to do with the surname. [2] \n\nSystematic (IUPAC) name \n1 Tadalafil at work \nRoutes ? \n\n[edit]\nCAS number 171596-29-5 \nDrugBank APRD00071 \nPregnancy cat. ?\nMetabolism ? \nTadalafil at work\nIn May 2005, the U.S. Food and Drug Administration found that tadalafil (along with other PDE5 inhibitors) could lead to vision impairment in certain patient groups, including diabetics. An investigation is currently ongoing.\n\nIn the United States, Eli Lilly has a multiyear agreement to promote tadalafil (Cialis) with professional golf's PGA TOUR.\n \n\nIt works by inhibiting an enzyme known as PDE5. A 20 mg dose of Tadalafil is comparable to a 100 mg dose of sildenafil (Viagra).\nTadalafil is a drug used to treat male erectile dysfunction (impotence). It was developed by the biotechnology firm ICOS and marketed worldwide by Eli Lilly and Company under the brand name Cialis.\nLegal status \n\n[edit]\nTadalafil \nDrug interactions - organic nitrates\n(Redirected from Cialis)\n[edit]\nHalf life 17.5 hours \n[edit]\n2 Chemical information \n3 Side effects \nTherapeutic considerations \n(6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1', 2':1,6] pyrido[3,4-b]indole-1,4-dione \nExcretion ? \nJump to: navigation, search\nTadalafil\nIdentifiers \n\n[edit]\nSince PDE5 inhibitors such as tadalafil may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of tadalafil. Using organic nitrates (such as the sex drug Amyl nitrite) within this timeframe may increase the risk of life-threatening hypotension.\n \n5 Marketing \n\n[edit]\nPubChem 110635 \nContents [hide]\nIn the United States, tadalafil has Food and Drug Administration approval and became available in December, 2003 as the third pill after Viagra and Levitra. Due to its 36-hour effect it is also known as the "Weekend Pill".\nMarketing\nBioavailability ? \nThe most common side effects when using tadalafil are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Patients who get back pain and muscle aches usually get it 12 to 24 hours after taking the drug, and the symptom usually goes away after 48 hours.\nProtein binding 94% \nChemical information\nFrom Wikipedia, the free encyclopedia\nPharmacokinetic data \nExternal links\n4 Drug interactions - organic nitrates \n+9483.642578125
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