Thanks. I only half-realized my answer would go out to all of livejournal (I don't normally answer the writer's block question), so I'm a little surprised somebody read it, haha.

It's just such a complex issue for a question as simplistic as this. I mean, historically women have really had the worse treatment, but at this point I don't think it's useful to try to sum up the experiences of two entire genders, place each on what must necessarily be opposite ends of the spectrum and weigh one as the more difficult life, especially because of a reason like "omg women have periods!" (as I see quite a few of the answers mention). Periods are a pain but saying they make a woman's life "worse" implies that men have the "better" or normal experience for not having periods, thus perpetuating the archaic notion that there's something inherently less-than about the lives of women. And, taa-daa, just like that the idea prevails that males and females are separate and unequal, thus continuing a sense of rivalry and hindering cooperation and understanding.

I'm not saying men and women don't have their own shit to deal with and various prejudices working against them, but it's not beneficial to think those define entire genders. Thinking in limited terms like "you're a man and therefore you have this and therefore your life is necessarily worse" (or whatever combination) is a very simple way to view and blanket social and cultural experience and obscure the more complex aspects of gender relations.