Made with Adobe Photoshop CS3. Not translatable.
Level: Hard. Uses selective coloring and curves.
1. Start by cropping the image to 100x100 px.
2. Layer > new adjustment layer > Curves
RGB
Input 1: 69
Output 1: 90
Input 2: 158
Output 2: 193
RED
Input: 72
Output: 81
GREEN
Input: 75
Output: 85
BLUE
Input: 150
Output: 169
3. Layer > new adjustment layer > color balance
Midtones: 19, 11, -30
Highlights: 18, 0, 15
4. Layer > new fill layer > #e6f9fb > soft light 100
5. Layer > new fill layer > #d4ecf3 > color burn 100
6. Duplicate base > drag to top > soft light 70
7. Layer > new adjustment layer > selective color
REDS
Magenta: 13
Yellow: 30
YELLOWS
Cyan: -30
Yellow: 20
NEUTRALS
Cyan: 15
Magenta: 10
Black: 10
8. Layer > new adjustment layer > hue/saturation > master saturation +25
9. Merge all layers
And you're done! Let me know what you think. :)