Oh. My. God.
House: Oh. My. God. You're not wearing underwear!
Cuddy: Of course I'm...
House: Skirt that tight, you've got no secrets. Skirt that tight, I can tell if you've got an IUD. You seen Dr. Cole?
Cuddy: No.
House: You're blushing.
Cuddy: I am not.
House: Look at me. Oh. My. GOD!
(4x08 You Don't Want To Know)