Восстановление дентина
В готовом к употреблению виде ничего нет, я просто оставляю, чтобы потом знать по каким ключевым словам искать. Речь идёт о заполнении кариозных дырок не цементами/полимерами, а о стимуляции прямо восстановления зуба. Это возможно только если зуб живой. О том, чтобы прямо выращивать новые зубы / заменить импланты речь не идёт.
Главный исследователь - Paul Thomas Sharpe https://en.wikipedia.org/wiki/Paul_Thomas_Sharpe.
Вот например интервью с ним https://youthtimemag.com/self-repairing-of-the-teeth-an-interview-with-professor-sharpe/
Материал называется ReDent - Inhibitor of GSK3 activity to stimulate dentine repair. Вот статья про материал, купить его здесь нельзя http://kingslicensing.kcl.ac.uk/technology/46596
https://en.wikipedia.org/wiki/Tooth_regeneration
https://en.wikipedia.org/wiki/Regenerative_endodontics
Ещё пара методов:
https://www.uab.edu/reporter/patient-care/advances/item/9814-no-filling-no-drilling-an-expert-s-guide-to-the-top-tooth-tech-of-2022
1) Насыщение смолой (Resin infiltration)
2) Биоактивные пломбы (Bioactive materials) - release calcium, phosphate and fluoride ions. Предотвращают пломбокариес, выпуская ионы кальция, фосфатов и фтора.
UPD 20/09/2023: О прямо выращивании новых зубов:
https://www.wionews.com/science/japan-scientists-developing-drug-to-regrow-teeth-trials-to-begin-in-july-2024-624592
https://mainichi.jp/english/articles/20230609/p2a/00m/0sc/026000c
researchers progressed to experiments aimed at blocking the expression of USAG-1
UPD 05/12/2023: https://medicalxpress.com/news/2023-12-scientists-tissue-regeneration-root-canal.html
Scientists work to bring tissue regeneration to replace root canal treatment
by Forsyth Institute
ADA Forsyth scientists are testing a novel technology to treat endodontic diseases (diseases of the soft tissue or pulp in your teeth) more effectively.
The study, "RvE1 Promotes Axin2+Cell Regeneration and Reduces Bacterial Invasion," which appeared in The Journal of Dental Research, demonstrates regenerative properties of resolvins, specifically Resolvin E1 (RvE1), when applied to dental pulp. Resolvins are part of a greater class of Specialized Proresolving Mediators (SPMs). This class of molecule is naturally produced by the body and is exquisitely effective in the control of excess inflammation associated with disease.
Study authors include Yu-Chiao Wu, Ning Yu, Carla Alvarez Rivas, Nika Mehrnia, and Alpdogan Kantarci.
More information: Y-C. Wu et al, RvE1 Promotes Axin2+ Cell Regeneration and Reduces Bacterial Invasion, Journal of Dental Research (2023). DOI: 10.1177/00220345231197156
Главный исследователь - Paul Thomas Sharpe https://en.wikipedia.org/wiki/Paul_Thomas_Sharpe.
Вот например интервью с ним https://youthtimemag.com/self-repairing-of-the-teeth-an-interview-with-professor-sharpe/
Материал называется ReDent - Inhibitor of GSK3 activity to stimulate dentine repair. Вот статья про материал, купить его здесь нельзя http://kingslicensing.kcl.ac.uk/technology/46596
https://en.wikipedia.org/wiki/Tooth_regeneration
https://en.wikipedia.org/wiki/Regenerative_endodontics
Ещё пара методов:
https://www.uab.edu/reporter/patient-care/advances/item/9814-no-filling-no-drilling-an-expert-s-guide-to-the-top-tooth-tech-of-2022
1) Насыщение смолой (Resin infiltration)
2) Биоактивные пломбы (Bioactive materials) - release calcium, phosphate and fluoride ions. Предотвращают пломбокариес, выпуская ионы кальция, фосфатов и фтора.
UPD 20/09/2023: О прямо выращивании новых зубов:
https://www.wionews.com/science/japan-scientists-developing-drug-to-regrow-teeth-trials-to-begin-in-july-2024-624592
https://mainichi.jp/english/articles/20230609/p2a/00m/0sc/026000c
researchers progressed to experiments aimed at blocking the expression of USAG-1
UPD 05/12/2023: https://medicalxpress.com/news/2023-12-scientists-tissue-regeneration-root-canal.html
Scientists work to bring tissue regeneration to replace root canal treatment
by Forsyth Institute
ADA Forsyth scientists are testing a novel technology to treat endodontic diseases (diseases of the soft tissue or pulp in your teeth) more effectively.
The study, "RvE1 Promotes Axin2+Cell Regeneration and Reduces Bacterial Invasion," which appeared in The Journal of Dental Research, demonstrates regenerative properties of resolvins, specifically Resolvin E1 (RvE1), when applied to dental pulp. Resolvins are part of a greater class of Specialized Proresolving Mediators (SPMs). This class of molecule is naturally produced by the body and is exquisitely effective in the control of excess inflammation associated with disease.
Study authors include Yu-Chiao Wu, Ning Yu, Carla Alvarez Rivas, Nika Mehrnia, and Alpdogan Kantarci.
More information: Y-C. Wu et al, RvE1 Promotes Axin2+ Cell Regeneration and Reduces Bacterial Invasion, Journal of Dental Research (2023). DOI: 10.1177/00220345231197156