I've saw this around a while back and I'm not going to go searching for it. Give me a TV Show/movie and I'll give you my first and second OTP and if I have one, I'll give you a bonus OTP. You can look at my interests list to get an idea of what I watch.
I just checked my profile and I really don't have a lot there...I must update.
persiflage_1 gave me:
Doctor Who
Doctor/Romana - Watch The Key to Time series and listen to Shada and you’ll understand why these two are still my OTP in Doctor Who. I must finish my Eight/Romana story.
Larry/Sally (Blink) - For the little time we saw them, they were awesome. I still think Sally would have made a great companion.
Bonus OTP: I have two. Doctor/Martha and Doctor/Sarah Jane - There was potential here for some awesomeness, but RTD’s Mary Sue/wank-tendencies got in the way and Martha’s characterization through out the series was sporadic. RTD and the writers did everything they could to keep Martha in Rose’s shadow and that was unfair. Martha was smart, brave, resourceful, and downright kick-ass. As for the second bonus OTP pairing, she’s Sarah Jane for crying out loud!
Torchwood
Jack/Everyone - Seriously! Jack can’t be with just one.
Gwen/Rhys - I really liked him in Children of Earth and you know that they teamed up to keep Torchwood going.
CSI
Grissom/Willows - The chemistry, the snark, the bantering, the arguments, the looks, the lines (“I miss your tush”), etc. She can talk to him as no one else can and he values her opinion. Not to mention, she’s the only one that walks into his townhouse without knocking and goes through his things while he’s getting ready for court. They’re MARRIED!
Grissom/Lady Heather - Lady Heather understands him better than anyone does. She helps him come to terms with his social issues and helps him realize what he really needs: SaraCatherine Willows. I don’t care what Petersen says, they friggin’ slept together before he betrays her. Stupid, stupid man (Grissom, not Petersen :P).
Bonus OTP: Nick/Kristy - they were really cute together. Besides, any girl who would put drugs on her nipples to knock guys out to rob them has got to be interesting in bed. ;)
Now for some silliness with all three:
Jack would go for everyone on CSI, especially Nick.
Doctor would want Lady Heather because he would find her fascinating, smart and very capable of taking care of herself. Plus, he secretly loves the black leather and fantasizes about the whip.