The aim of this study was to access the role of acid, weakly-acid and alkaline reflux in esophageal mucosal injury.
127 patients, 75 women and 52 men, off acid-suppressive therapy underwent upper-GI endoscopy with biopsy and combined esophageal pH-impedance monitoring. According to data from pH-impedance study patients were subdivided into three groups by predominant characteristic of reflux: GERD with acid reflux (AR); GERD with weakly-acid reflux (WR); GERD with duodenogastroesophageal reflux (DGER)
Fig I. Results of upper-GI endoscopy in GERD patients with different types of reflux
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Kaibysheva V., Trukhmanov A., Ponomarev A., Storonova O., Konkov M., Ivashkin V. Role of acid and non-acid reflux esophageal mucosal damage / 22-nd United European Gastroenterology Week October 18 - 22, 2014. Vienna, Austria.