Ahem.
This...I thought this was a joke at first. I even registered with IMDB so I could check out the comments section.
It's a barrel full of rofl.
Sequels:
Snakes on a Plane 2: Planes on a Snake
Year 2060. The US Army now uses giant snakes as army bases. The biggest snake-base, Sssrah!, is being attacked by giant bees. It's the 5 snake's best pilots job to go out and defend the snake from the bees in their supersonic snake venom powered jet.
Snakes on a Plane 3: Plakes on a Snane
A non-sensical charming romp through the coma induced dreams of a 12 year old retarded boy. It could have a shocking twist towards the end revealing that the boy became retarded after watching Snakes on a Plane and it's sequels. And he's in a coma because he got hit by a truck... full of snakes...
Snakes on a Plane 4: Snakes on a Plain
Like the award-winning Kevin Bacon film, "Tremors." But more snakes.
Snakes on a Plane 5: Snakes Plain
People all over the world begin ordering the Snake Sandwich *WITHOUT ONIONS!* (Queue the dissonate cello) Sparks fly with William Peterson and David Caruso starring as a team of forensic investigators trying to smell out the cause of this baffling mystery.
Snakes on a Plane 6: Snakes with Planes
Evil Pentagon scientists develop brain wave operated fighter planes, which fall into the hands of super-intelligent laboratory snakes, (whose genes have been spliced.) Revenge is on their reptillian brains for what happened in "Snakes on a Plane 5: Snakes Plain" For the first time in history snakes can
work the throttle, control stick, rudder pedals and missile fire control systems simultaneously. (BTW wasn't there a...Jessica Alba movie like this or something?)
Etc. Due credit to the OPs.