Biodamp
So canon says Ten loved Rose. In light of that, how significant is the biodamping scene in The Runaway Bride? I don't necessarily mean in a shippy way, but symbolically, between the two characters and the intertwining of their fates. Rose may have been linked to Ten the man, but it seems to me The Doctor, being a Time Lord (and all that entails) was more significantly linked to Donna than Rose ever could be.