Day three! A bit late, but still the same day for me. (I haven't gone to sleep yet!)
So for my choice for favorite female in a comedy show ...
Margaret Houlian from M*A*S*H. She is another character who's strengths are never lessened as the show progresses. She is just as amazing a character from the first ep to the last. She too has some great development that enhances and deepens her charcter, but never changes her from who she always was. She's smart, she's funny, shes gusty, strong, emotional and independent. And I will admit, I always kinda shipped Hawkeye/Margaret. :)