I worked in honeybee research for three years (in Michigan) and we maintained about fifty hives. IIRC, we found foul brood once during those three years; those hive boxes and frames had to be autoclaved.
We treated with terramycin and in general it was effective; I would recommend it.
Yes, autoclaving is effective as long as it's done properly. Some beekeepers don't have easy access to a large autoclave though, so in those cases the most sure-fire way is, indeed, to incinerate the infected boxes and frames.
We had a sister department that didn't bother autoclaving; they did incinerate theirs.
Sorry, I should clarify: we cleared out the hives first and scraped all the foul brood. The empty boxes and frames were then claved. So yes, you still need to start over, in effect. Autoclaving is only useful if it's important to you to salvage your equipment.
We treated with terramycin and in general it was effective; I would recommend it.
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We had a sister department that didn't bother autoclaving; they did incinerate theirs.
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