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Apr 21, 2005 20:23

"As the rectum fills with feces, the smooth muscle wall of the rectum contracts and the internal anal sphincter relaxes in the rectosphincteric reflex. Defecation will not occur at this time, however because the external anal sphincter (composed of striated muscle and under voluntary control) is still tonically contracted. However, once the ( Read more... )

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baslug April 22 2005, 02:21:31 UTC
Vasopressin (Antidiuretic Hormone, ADH), is the major hormone concerned with regulation of body fluid osmolarity. When the body is deprived of water, blood serum osmolarity increases. This increase is sensed by osmoreceptors in the hypothalamus which in turn propogates signals to secrete ADH. The major action of ADH is to increase water permeability to allow water to be reabsorbed by the collecting ducts of the kidneys and thereby concentrating the urine. Converse to the secretion of ADH, a decrease in serum osmolarity (by drinking enough water) signals the hypothalamic osmoreceptors to inhibit the secretion of ADH. Inhibition of ADH just means that no more new ADH is being released...you still have some in the blood stream and it takes about an hour for it to clear out.

So even though your blood osmolarity is low you dont know it because of all the ADH in your blood...so you keep chugging those beers thinking your bladder is okay. after an hour, the ADH wears off and you realize you have to go pee. So you go, and since youre blood has more fluid than it needs, none of the fluid from those extra beers you drank is getting absorbed...so you have to pee again within about 10 to 15 minutes. hence, you've "broken the seal."

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