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This one's hard. Everyone likes a dozen different bands. How do you pick between your current favorite and a classic, like the Beatles or Led Zeppelin? They're all great.
Muse and the Yeah Yeah Yeahs were definitely contenders, but Franz Ferdinand will always be the coolest guys on the planet - there's no album where they suddenly forgot the guitars, no sinkhole of cheesy tabloid fodder. They always make me joyful - they made the art of making sad and broken sound good.
Plus, I mean, pssht, look how friggin' hot they are.