You may have heard of Dr. Randy Pausch. He recently gave a lecture at Carnegie Mellon University. Dr. Pausch knew he was dying of Pancreatic cancer when he gave a lecture in a series of professors giving their "Last lecture..."
He recently gave an eleven minute version of this lecture on Oprah. I think it's well worth watching if you haven't yet.
http://video.stumbleupon.com/?s=ithct48cqw&i=ufcchmyxqsuj9vwsemax You can find the original lecture on YouTube.