Myostatin Deficiency Mutation

Feb 07, 2012 17:36



        I am still working on a sequel to Coconuts: Civilizer of Mice and Humans, which I made early this past January.  While looking for images of Mighty Mouse, I discovered a website dealing with Myostatin Deficiency.  It would appear that my experiment with Civilizing Mice has resulted in Some mice looking like body builders, who are decidedly more muscular and twice the size of normal mice.  No change in size of older mice, but pregnant mice who lived on the diet I provided them were huge during pregnancy and their offspring look more like chipmunks on Steroids than mice.



I am reminded of H.G.Wells' book, Food of the Gods.  Is it possible that I have inadvertently discovered the Food of the Gods?

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Muscle in a myostatin-deficient mouse; left, facial muscles, right, forelimb. Top is a normal mouse, bottom is a mouse expressing the mutant phenotype.



Scientists are able to delete the myostatin gene in mice. This is the result.



A muscle ‘explosion’ follows myostatin ‘neutralization’. The control mouse (normal) is shown for comparison. The ActRIIB mice have a genetic defect that prevents myostatin from binding to its purported receptor. Follistatin mice are genetically modified to express high levels of follistatin; this also results failure of myostatin to bind to its receptor. The result in both cases is dramatically enhanced muscle mass. Similar studies indicate large reductions in body fat. Strength and caloric output also increase markedly.



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Meet the German baby Superman.



Before he was 5 years old, he could hold 7 lbs. weights with arms extended, something many adults cannot do. He has muscles twice the size of other kids his age and half their body fat.       



He was born to a somewhat muscular mother, a 24-year-old former professional sprinter. Her brother and three other close male relatives all were unusually strong, with one of them a construction worker able to unload heavy curbstones by hand.



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Meet Liam Hoekstra.

A 21 month old toddler from Michigan with myostatin deficiency, he has 40 percent more muscle mass than normal, jaw-dropping strength, breathtaking quickness, a speedy metabolism and almost no body fat. Liam came into the world with many birth defects. He had a small hole in his heart, enlarged kidneys, frequently vomited and was born four weeks premature. Medical records indicated that his biological father was “unusually strong.”



“He could do the iron cross when he was 5 months old,” said his adoptive mother, Dana Hoekstra of Roosevelt Park. She was referring to a difficult gymnastics move in which a male athlete suspends himself by his arms between two hanging rings, forming the shape of a cross.



Two days after birth, he was able to fully stand-up and support his own weight. Months later, he began developing ripped abs, naturally doing pull-ups, inverted sit-ups, Olympic styled iron crosses, thigh muscles compared to that of Lance Armstrong and even punching holes into walls during tantrums (he accidentally gave his Mom a black eye once as well).



http://www.who-sucks.com/people/monstrous-myostatin-misfortunes-a-collection-of-myostatin-deficiency-pictures

food of the gods, coconut oil, pistachio nuts

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