(Taken from
http://folding.stanford.edu/)
Our goal: to understand protein folding, misfolding, and related diseases
What is protein folding and how is folding linked to disease?
Proteins are biology's workhorses -- its "
nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "
fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.
Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known
diseases, such as
Alzheimer's, Mad Cow (BSE), CJD, ALS,
Huntington's,
Parkinson's disease, and many
Cancers and cancer-related syndromes.
You can help by simply running a piece of software. Folding@Home is a distributed computing project -- people from through out the world
download and run software to band together to make one of the largest supercomputers in the world. Every computer makes the project closer to our goals.
Folding@Home uses novel computational methods coupled to distributed computing, to simulate problems thousands to millions of times more challenging than previously achieved.
Folding@Home SMP client (with native OSX/Intel support) now in beta testing phase CURRENT PROJECTS AND PROGRESS TO DATE:
Your participation can help lead to a cure for these diseases.
Click
here for free download.
Results from
Folding@Home What have we done so far? We have had several successes. You can read about them on our
Science page,
Results section, or go directly to our
press and papers page.
Want to learn more? Click on the links on the left for downloads or more information. You can also download our
Executive Summary, which is a PDF suitable for distribution. Also, you can learn more by watching recent seminars (
Stanford BMI ;
Xerox PARC). One can also help by
donating funds to the project, via Stanford University.
Since October 1, 2000, over 1,000,000 CPUs
throughout the world have participated in Folding@Home. Each additional CPU gives us an added boost in performance, allowing us to tackle more difficult problems or solve existing research faster or more accurately.
Is English not your native language? We also have translations for the
Chinese,
Dutch,
French,
German,
Italian, Japanese,
Korean,
Persian,
Polish,
Portuguese,
Russian,
Spanish, and
Vietnamese (also see the links at the top of the page).