Posted by CN Staff on June 01, 2006 at 13:19:12 PT
Weekly Press Release
Source: NORML
Cannabidiol Dramatically Inhibits Breast Cancer Cell Growth, Study Says
June 1, 2006 - Naples, Italy
Naples, Italy: Compounds in marijuana inhibit cancer cell growth in animals and in culture on a wide range of tumoral cell lines, including human breast carcinoma cells, human prostate carcimona cells, and human colectoral carcinoma cells, according to preclinical trial data published in the May issue of the Journal of Pharmacology and Experimental Therapeutics.
Investigators at Italy's Instuto di Chemica Biomolecolare assessed the anti-cancer activity of various non-psychoactive cannabinoids - including cannabidiol (CBD), cannabigerol (CBG), and cannabichromine (CBC) - in vivo and in vitro. Researchers reported that CBD acts as a more potent inhibitor of cancer cell growth than other cannabinoids, including THC, and noted that the compound is particularly efficacious in halting the spread of breast cancer cells by triggering apoptosis (programmed cell death).
Cannabigerol and CBC also possess anti-tumor properties, but lack the potency of CBD, they found.
"These results suggest the use in cancer therapy for cannabidiol," investigators concluded.
Previous studies have shown cannabinoids to reduce the size and halt the spread of glioma (brain tumor) cells in animals and humans in a dose dependent manner. Separate preclinical studies have also demonstrated cannabinoids to inhibit cancer cell growth and selectively trigger malignant cell death in skin cancer cells, leukemic cells, lung cancer cells, and prostate carcinoma cells, among other cancerous cell lines.
For more information, please contact Paul Armentano, NORML Senior Policy Analyst, at (202) 483-5500. Full text of the study, "Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma," is available online at:
http://jpet.aspetjournals.org/cgi/reprint/jpet.106.105247v1 Additional information on cannabinoids' anti-cancer properties is available in NORML's report, "Cannabinoids as Cancer Hope," online at:
http://norml.org/index.cfm?Group_ID=6814 DL:
http://norml.org/index.cfm?Group_ID=6917 Seems like study after study says that same thing. Cannabis use seems to offer relief from the symptoms of almost every major illness, and actually helps fights many others. The list just keeps on growing. So why does the FDA claim there is no medical use and that cannabis smoke is bad for you? Studies have shown that even long term heavy cannabis use causes NO increase in cancer risk, and actually lowers the risk of respiratory cancer in people who don't smoke cigarettes. Now we know why. Cannabis actually fights cancer, and this is at least the third major study I've seen that demonstrates this.